# Scientists Create AI Tool to Predict Cancer Spread
Researchers at the University of Geneva have developed an artificial intelligence program that can predict whether cancer will spread to other parts of the body, a process called metastasis. This breakthrough could help doctors provide better treatment for cancer patients.
## Understanding Cancer Spread
Metastasis occurs when cancer cells break away from the original tumor and form new tumors elsewhere in the body. This process causes most cancer deaths. Scientists have struggled to understand why some cancer cells spread while others stay in one place. The research team discovered that cancer follows specific patterns that can be identified and predicted rather than being random.
## How the Research Worked
The scientists studied colon cancer cells by isolating and growing individual cell clones in the laboratory. They analyzed how hundreds of genes were expressed, meaning turned on or off, in these cells and tested their ability to migrate or move through tissue. They found that groups of related cancer cells working together, rather than single cells alone, determine whether metastasis will occur.
## The MangroveGS Algorithm
Using their findings, the team created an AI tool called MangroveGS, short for Mangrove Gene Signatures. This program analyzes patterns from dozens or hundreds of genes to predict metastasis risk. In testing, it achieved nearly 80% accuracy in predicting colon cancer spread and recurrence, performing much better than existing methods. The tool also works for other cancers including stomach, lung, and breast cancer.
## Benefits for Patients
Doctors can now analyze tumor samples and receive risk scores through a secure online portal. This helps them avoid overtreating low-risk patients while providing intensive care for high-risk patients, improving outcomes while reducing unnecessary side effects and costs.